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This guideline discusses the diagnosis, investigation and management of patients with solitary plasmacytoma of bone, extramedullary plasmacytoma and multiple solitary plasmacytomas.

It was updated in 2009 to include newly available information on diagnosis, prognosis and management, in particular the role of serum free light chains (SFLCs) and PET scanning.

It also included a new section on the management of multiple solitary plasmacytomas.

This guideline has an update please see the information below.

Declaration of Interests

The BSH paid the expenses incurred during the writing of this guidance. None of the authors had conflicts of interest to declare. All authors have made a declaration of interests to the BSH and Task Force Chairs which may be viewed on request.