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UK Myeloma Forum (UKMF) and Nordic Myeloma Study Group (NMSG): Guidelines for the investigation of newly detected M-proteins and the management of Monoclonal Gammopathy of Undetermined Significance (MGUS) 

This is a joint guideline produced by the UK Myeloma Forum and Nordic Myeloma Study Group. It discusses:

  • When to test for an M protein
  • Identification of an M protein and appropriate laboratory investigations
  • Investigation of patients with newly detected M proteins
  • Diagnostic criteria and differential diagnosis of MGUS from myeloma, other plasma cell dyscrasias or Waldenstrom’s macroglobulinaemia
  • Management of MGUS

Declaration of Interests

The BSH paid the expenses incurred during the writing of this guidance. None of the authors had conflicts of interest to declare. All authors have made a declaration of interests to the BSH and Task Force Chairs which may be viewed on request.