To provide healthcare professionals with clear guidance on situations when the use of irradiated blood components is appropriate, and to document any recognised advantages and disadvantages of their use. The guidance may not be appropriate in all patient situations, and individual circumstances may dictate an alternative approach. Studies of patients in all age groups have been considered.

Declaration of Interests

The BSH paid the expenses incurred during the writing of this guidance. None of the authors had conflicts of interest to declare. All authors have made a declaration of interests to the BSH and Task Force Chairs which may be viewed on request.