A genetic investigation into the increased risk of leukaemia among people with Down’s syndrome has provided new insights into the disease, scientists say.
People with Trisomy 21, also known as Down’s syndrome, have an increased risk of developing blood cancers including acute megakaryoblastic leukaemia and acute lymphoblastic leukaemia. However, at the same time there is a lower prevalence of solid tumours amongst people with Down’s syndrome. A team led by researchers from Lurie Children’s Hospital of Chicago, USA, set out to investigate whether endothelial cells might provide a clue to this unique clinical picture.
Mariana Perepitchka and Yekaterina Galat from of Lurie Children’s and colleagues used skin samples from...
4 days ago
A genetic investigation into the increased risk of leukaemia among people with Down’s syndrome has provided new insights into the disease, scientists say.
People with Trisomy 21, also known as Down’s syndrome, have an increased...
4 days ago
Two tests have proved equally useful at deciding which patients with acute pulmonary embolism can be managed at home, a European conference has heard.
Haemodynamically stable acute pulmonary embolism patients are often kept in...
4 days ago