Venous thromboembolism (VTE) and bleeding are serious complications of cancer and its treatment. A recent survey of UK paediatric haematologists and oncologists identified a broad variety of practice in the management of issues relating to these complications in children with leukaemia, reflecting significant areas of uncertainty (Biss et al2016a2017). The purpose of this guideline is to provide information and guidance on the management of these issues in children being treated for leukaemia and other forms of cancer. The following areas are covered:

  • Assessment and reduction of the risk of VTE
  • Treatment of the various types of VTE
  • Management of thrombocytopenia and coagulopathy
  • Therapy for menstrual suppression

Declaration of Interests

The BSH paid the expenses incurred during the writing of this guidance. None of the authors had conflicts of interest to declare. All authors have made a declaration of interests to the BSH and Task Force Chairs which may be viewed on request.