New research has offered fresh insights into how blood clots form in some people with COVID-19. The US study suggests that the life-threatening blood clots and inflammation are driven by overactive neutrophils in the immune system.
The research was led by Drs Joshua Schiffman and Christian Con Yost of the University of Utah, with collaborators at PEEL Therapeutics, Cold Spring Harbour Laboratory and Weill Cornell Medicine.
They explain that ‘neutrophil extracellular traps’, or NETs, are produced by neutrophils to capture and destroy viruses and bacteria. But too many can accumulate during a persistent infection, and trigger immunothrombosis, leading to acute respiratory distress syndrome.
The researchers took a closer l...
1 day ago
New research has offered fresh insights into how blood clots form in some people with COVID-19. The US study suggests that the life-threatening blood clots and inflammation are driven by overactive neutrophils in the immune syste...
1 day ago
Scientists have revealed a possible explanation for why the drug nelarabine, given for T cell acute lymphoblastic leukaemia (T-ALL), is not as successful against B-cell ALL.
The molecular mechanisms underlying this difference hav...
1 day ago